Gyrospun antimicrobial nanoparticle loaded fibrous polymeric filters.

Synthesis, Characterization, and In Vivo Efficacy of Shell Cross-Linked Nanoparticle Formulations Carrying Silver Antimicrobials as Aerosolized Therapeutics

The use of nebulizable, nanoparticle-based antimicrobial delivery systems can improve efficacy and reduce toxicity for treatment of multi-drug-resistant bacteria in the chronically infected lungs of cystic fibrosis patients. Nanoparticle vehicles are particularly useful for applying broad-spectrum silver-based antimicrobials, for instance, to improve the residence time of small-molecule silver ...

Silver Nanoparticle Loaded Activated Carbon: An Escalated Nanocomposite with Antimicrobial Property

In this work, the antimicrobial property of nanocomposite prepared by loading of silver nanoparticle onto activated carbon (AgNP-AC) was studied. The silver nanoparticles were synthesized biologically from the culture Enterobacter aerogenes and loaded onto the activated carbon. The nanoparticle and nanocomposite were characterized by UV-vis, scanning electron microscopy and X-ray diffraction st...

Rivastigmine-Loaded L-Lactide-Depsipeptide Polymeric Nanoparticles: Decisive Formulation Variable Optimization

The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer for the development of rivastigmine-loaded polymeric nanoparticles. L-lactide-depsipeptide synthesis was based on the ring opening polymerization reaction of L-lactide with the cyclodepsipeptide, cyclo(Glc-Leu), using tin 2-ethyl hexanoate as an initiator. Rivastigmine-loaded nanoparticles were prepared by...

Fabrication of Bovine Serum Albumin-Loaded Coaxial Electrospun Thread with an Aligned Core-Shell Fibrous Structure

Preparation and Evaluation of Poly (s-caprolactone) Nanoparticles-in- Microparticles by W/O/W Emulsion Method

Objective(s) Theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. It is used both as a prophylactic drug and to prevent acute exacerbations of asthma. The aim of study was to formulate and evaluate effect of the microencapsulation of theophylline loaded nanoparticles on the reduction of burst release. Materials and Me...